Gianpaolo Papaccio: Difference between revisions
No edit summary |
No edit summary |
||
| Line 32: | Line 32: | ||
Over the years, he has held numerous teaching courses in the said Universities, becoming, since 2013 President of the Degree Course in Medicine and Surgery in English for foreigner and Italian students. This Position was maintained up to 2019. | Over the years, he has held numerous teaching courses in the said Universities, becoming, since 2013 President of the Degree Course in Medicine and Surgery in English for foreigner and Italian students. This Position was maintained up to 2019. | ||
== Research Interests == | |||
Gianpaolo Papaccio’s research interests include: Human mesenchymal stem cell (hMSC) biology from isolation to characterization and differentiation into osteogenic, angiogenic and adipogenic lineages. Production in vitro and in vitro of Human bone starting from hMSCs, studies of stem cell adhesion and differentiation to several scaffolds for bone tissue engineering, relationship between hMSCs and cancer stem cells (CSCs) in the tumor bulk of human osteosarcomas and breast cancers and peritumoral tissue, as well as mitochondrial transfer between hMSCs and CSCs. | |||
== Research == | |||
=== Studies on Human Mesenchymal Stem Cells === | |||
Gianpaolo Papaccio’s studies on Human Mesenchymal stem cells include stem cells from adipose Stromal-Vascular area of Human adipose tissue, taken from patients undergoing plastic surgery or from dental pulps of patients undergoing 3rd molar surgery. Those studies were performed in his laboratory and in collaboration with other research Labs. The studies were the first ones demonstrating that Dental Pulp Stem Cells (DPSCs) were capable to give rise to woven bone in in vitro culture<ref>Papaccio G, Pisanti F.A. and Frascatore S.: [https://diabetesjournals.org/diabetes/article/35/4/470/7827/Acetyl-Homocysteine-Thiolactone-Induced-Increase Acetyl- homocysteine thiolactone-induced increase of Superoxide Dismutase counteracts the effect of subdiabetogenic doses of streptozocin]. ''Diabetes'', 35, 470-474, 1986</ref><ref>Papaccio G., Esposito V.: [https://link.springer.com/article/10.1007/BF02742965 Hyperglycemic effects of hydrochlorothiazide and propranolol. A biochemical and ultrastructural study]. ''Acta Diabetologica Latina,(oggi Acta Diabetologica)'' 24, 325-330, 1987</ref> and then, when grafted to patient’s mandible, able to obtain a compact bone<ref>Esposito V. and Papaccio G.: [https://www.sciencedirect.com/science/article/abs/pii/0739626088900147 Nephrotoxicity of Cyclosporin A in diabetic Bio Breeding rats], ''Micron'', 19, 227-234, 1988</ref><ref>Pisanti F.A., Frascatore S., Papaccio G.: [https://www.sciencedirect.com/science/article/abs/pii/0024320588905346?via%3Dihub Superoxide dismutase activity in the Bio Breeding rat: a dynamic time-course study]. ''Life Sciences'', 43, 1625-1632, 1988</ref>. | |||
== External links == | == External links == | ||
Revision as of 12:14, 21 December 2022
Gianpaolo Papaccio was born in Napoli (Italy) in 1955. He obtained his BA in Medicine and Surgery cum laude in 1979 at the Federico II University of Naples and his Ph.D. in Human Biostructure at the Washington University of Seattle (Seattle, WA, USA) in 1982.
| Born | February 13th, 1955 Napoli, Italy |
| Nationality | Italian |
| Education | University of Naples “Federico II” (Italy) Washington University -Seattle (USA) |
| Fields | Medicine and Surgery |
| Institutions | University of Campania “L. Vanvitelli” Medicine and Surgery School-Naples (IT) |
| Notes | |
| Top Italian Scientist in Biomedical Sciences | |
Positions
He is currently Full Professor of Human Histology and Embryology, at the Department of Experimental Medicine, University of Campania “L. Vanvitelli” Naples. He is a member of the Ph.D. Council of Biotechnology at the same University.[1]
Education and career
Gianpaolo Papaccio graduated in Medicine and Surgery from the University Naples “Federico II” in 1979. He got a Ph.D. from the University of Washington (Seattle-USA) with a research project on the 3D reconstruction of pancreatic islets from healthy and type 1 diabetic subjects. political-economic cycle. He got a position as a Researcher in 1984 in the University of Naples “Federico II”. In 1994 he was appointed as associate professor at the same University and in 2005 he become Full Professor of Human Histology and Embryology at the University of Campania “L. Vanvitelli”.
At the same time he was also physician in the Clinical Hospital of the University as assistant, then Head of the Hospital Division of “Citometry and NGS” for Oncological patients.
Over the years, he has held numerous teaching courses in the said Universities, becoming, since 2013 President of the Degree Course in Medicine and Surgery in English for foreigner and Italian students. This Position was maintained up to 2019.
Research Interests
Gianpaolo Papaccio’s research interests include: Human mesenchymal stem cell (hMSC) biology from isolation to characterization and differentiation into osteogenic, angiogenic and adipogenic lineages. Production in vitro and in vitro of Human bone starting from hMSCs, studies of stem cell adhesion and differentiation to several scaffolds for bone tissue engineering, relationship between hMSCs and cancer stem cells (CSCs) in the tumor bulk of human osteosarcomas and breast cancers and peritumoral tissue, as well as mitochondrial transfer between hMSCs and CSCs.
Research
Studies on Human Mesenchymal Stem Cells
Gianpaolo Papaccio’s studies on Human Mesenchymal stem cells include stem cells from adipose Stromal-Vascular area of Human adipose tissue, taken from patients undergoing plastic surgery or from dental pulps of patients undergoing 3rd molar surgery. Those studies were performed in his laboratory and in collaboration with other research Labs. The studies were the first ones demonstrating that Dental Pulp Stem Cells (DPSCs) were capable to give rise to woven bone in in vitro culture[2][3] and then, when grafted to patient’s mandible, able to obtain a compact bone[4][5].
External links
- Gianpaolo Papaccio - Università degli Studi della Campania "Luigi Vanvitelli"
- Gianpaolo Papaccio - Google Scholar
References
- ↑ Gianpaolo PAPACCIO - Università degli Studi della Campania "Luigi Vanvitelli"
- ↑ Papaccio G, Pisanti F.A. and Frascatore S.: Acetyl- homocysteine thiolactone-induced increase of Superoxide Dismutase counteracts the effect of subdiabetogenic doses of streptozocin. Diabetes, 35, 470-474, 1986
- ↑ Papaccio G., Esposito V.: Hyperglycemic effects of hydrochlorothiazide and propranolol. A biochemical and ultrastructural study. Acta Diabetologica Latina,(oggi Acta Diabetologica) 24, 325-330, 1987
- ↑ Esposito V. and Papaccio G.: Nephrotoxicity of Cyclosporin A in diabetic Bio Breeding rats, Micron, 19, 227-234, 1988
- ↑ Pisanti F.A., Frascatore S., Papaccio G.: Superoxide dismutase activity in the Bio Breeding rat: a dynamic time-course study. Life Sciences, 43, 1625-1632, 1988
