Maurizio Cutolo

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Maurizio Cutolo
Maurizio Cutolo, MD. University of Genova Medical School.
Email: mcutolo@unige.it
mobile: +39 335233621
office: +39 010 353 7994

Education

  • 1978: Degree in Medicine and Surgery, Thesis: Pathophysiology af Vasculitis - 110/110 magna cum laude, University of Naples - Naples - IT
  • 1982: Postgraduate Specialty on Rheumatology, Thesis: Rheumatoid arthritis - 50/50 magna cum laude, University of Genova - Genova - IT
  • 1982-1983: Outside Resident, Division of Rheumatology Bellevue Hospital New York University New York USA (Mentor G. Weissmann). Supported by an Educational fellowship bursary/Grant of the Italian Society for Rheumatology
  • 1986-1987: Outside Resident, Division of Rheumatology Bellevue Hospital New York University New York USA (Mentor S. Abramson). Supported by an Educational Grant from the Italian Society for Rheumatology
  • 1987: Postgraduate Specialty on Internal Medicine, Thesis: Trace elements in rheumatic diseases - 50/50 magna cum laude, University of Genova - Genova - IT

Academic positions

  • 1981 - 1997: Assistant Professor on Rheumatology, Institute of Science in Internal Medicine (ISMI) then Dept. Internal Medicine and Specialties, (DiMI) Medical School - University of Genova
  • 1998 - 2002: Associate Professor on Internal Medicine, Dept. Internal Medicine and Specialties DiMI University of Genova, Chief of Research Laboratories and inpatient out patients clinics
  • 1999 – ongoing: Director Research Laboratories on Experimental Rheumatology, Dept. Internal Medicine and Specialties DiMI Medical School - University of Genova
  • 2001 – 2023: Chief Division of Rheumatology and associatied Clinics University Hospital IRCCS San Martino Genova
  • 2003 - 2023: Director Postgraduate School of Rheumatology, Dept. Internal Medicine and Specialties DiMI Medical School - University of Genova
  • 2002 – ongoing: Full Professor of Rheumatology, Dept. Internal Medicine and Specialties DiMI Medical School - University of Genova
  • 2013 - ongoing: Founder and ongoing member of the Board of the PhD Program on Clinical and Experimental Immunology Medical School University of Genova
  • 2023 - ongoing: Professor Emeritus at University of Genova, Appointed by the Italian Ministry of University and Research – Rome
  • 2023 – ongoing: Senior Consultant Division of Rheumatology and associatied Clinics
  • 2023 – ongoing: Director Research Laboratories of Experimental Rheumatology University of Genova

Honorary Degrees

  • 2010: Budapest Appointed Honorary Member of the Hungarian Association of Rheumatologists during the National Congress by the President of the Hungarian Society, 23 September 2010
  • 2010: Moscow Appointed Honorary of the Russian Society for Rheumatology during the National Congress of the Society in Sankt-Peterburg (Russia) 26-29 October 2010
  • 2014 Bucharest LAURIS Doctor Honoris Causa in Medicine appointed in Bucharest by the Senatus and Rector (Prof. Joanel Sinescus) following Lectio Magistralis – State University “Carolus Davila” – Bucharest (Romania) 29 and 30 May 2014
  • 2017: Zurich Appointed Honorary Member of the European Alliance of Association for Rheumatology (EULAR) during the 70th Annual Congress in Madrid (Spain) 14-17 June 2017
  • 2024: From the American College of Rheumatology (ACR) and the Association of Rheumatology Professionals (ARP) Membership and Awards Committee, MC received the ACR Master Designation as AWARD winner and presented during the Opening Ceremony of the 2024 ACR Annual Meeting (15th November in Washington).
  • 2024/2027: On behalf of the American College of Rheumatology (ACR) and the ACR Global Engagement Committee, we would like to sincerely congratulate you on being selected for to the role of ACR International Adviser.

Working Experiences and Achievements

  • 1999 - 2018: Study Group on NeuroEndocrine Immunology (NEI) at the American College of Rheumatology (ACR) Annual Meeting. This study group had a good tradition in the ACR and has been founded and approved at ACR in 1999 (ACR Boston MA, by Prof. Dr. Alfonse Masi, Peoria (ACR Master) and Prof. Dr. Maurizio Cutolo (Genoa, Italy). Since then, several internationally recognized colleagues were coordinator of the study group during the years: starting A. Masi, 1999 - 2001; M. Cutolo, Genoa, Italy 2002 - 2004 and others. The meetings of the NEI SG were organized from 1999 (ACR Boston MA, November) until November 2018 (ACR Chicago,IL November) and were replicated every year at the Annual ACR meeting. The number of attendees was always in the range of 50-80 people but it exceeded the number of 100 people in 2008. The study group was alway well accepted by many colleagues in Rheumatology and Clinical Immunology at ACR because it bridged the different disciplines of Immunology, Endocrinology, and Neuroscience. M. Cutolo was also invited speaker in 12 of the 18 NEI sessions during the Annual ACR Meeting.
  • 1999 - 2021: Appointed Scientific Board Member of the American Autoimmune Related Diseases Association (AARDA) 22100 Gratiot Ave. Eastpointe, MI 48021 USA
  • 2004 - 2007: Elected Vice President of the Italian Society for Rheumatology
  • 2003 - 2007: Elected Member of the Scientific Committee of the European League Against Rheumatic Diseases (EULAR)
  • 2008 - 2015: Appointed Member of the Executive Committee of the International Society for Neuroimmunomodulation (ISNIM)
  • 2009 - 2011: Elected Chairman of Standing Committee for Education and Training (ESCET) of the European League Against Rheumatic Diseases (EULAR)
  • 2010: Executive President of the 11th Annual Congress of the European League Against Rheumatism (EULAR) Rome, Italy (June 16 - 19, 2010)
  • 2012 - 2018: Study Group on Capillaroscopy in Rheumatic Diseases at the American College of Rheumatology (ACR). The Study Group at ACR Annual Meeting was founded by M Cutolo (Genoa Italy) and A. Herrick (UK) in 2012 and approved by ACR at the 2012 at Annual ACR Meeting (Washington, DC) November 9-14, 2012. The SG Sessions were attended every ACR annual Meeting by an average number of 80-120 people and the structure was characterized by teoterical lessions and practical instrumental sessions. M Cutolo has been the coordinator every Annual ACR Meeting from November 2012 (ACR Washighton DC) until November 2019 (ACR Atlanta,Georgia November)
  • 2013 - ongoing: Appointed Deputy Chair of the European Rare Diseases Network (ERN) on Rare and Complex Connective Tssue Diseases (ReCONNET)
  • 2013-2015: Member of the EULAR Foundation for Research FOREUM
  • 2011-2013: President-elect of the 16th European League Against Rheumatic Diseases (EULAR) and member of Steering Group
  • 2013-2015: M Cutolo served as Full President of the European League Against Rheumatic Diseases (EULAR) for a period of 3 years
  • 2014-2015: M Cutolo has been appointed at the ACR Meeting in 2014 and has served as Chairman of the International League of Associations for Rheumatology (ILAR) managing the ILAR Committee meetings during the ACR annual Meeting in 2014 and 2015. The Associations/Ligues participating were represented by the relative Presidents of ACR , EULAR, PANLAR, APLAR, and AFLAR
  • 2011-2017: M Cutolo as Elect/Full/Past EULAR President was effective/operative Member of the Joint ACR and EULAR Executive Committee meetings during the Annual ACR Meetings from 2011 up to 2017
  • 2014: During the year 2014, some disagreements between ACR and EULAR arised. The President of ACR (J. Flood) and the President of EULAR (M.Cutolo) after mutual agreement produced/signed (April, 15 2014) on behalf of the ACR and EULAR a DOCUMENT OF RESOLUTION OF DISPUTES
  • 2015: Executive President of the 11th Annual Congress of the European League Against Rheumatism (EULAR) Rome, Italy (June 10-13, 2015)
  • 2016 - ongoing: Appointed member of the Steering Committe of the Immune Mediated Inflammatory Disease FORUM IMID (alias CSF forum) www.imidforum.com
  • 2017 - ongoing: Appointed Advisor of the Education Committee the EULAR School of Rheumatology (ESoR)
  • 2023 - ongoing: Appointed Member of the Medical and Scientific Advisory Council of the Autoimmune Association USA (world’s leading nonprofit dedicated to autoimmune awareness, education, advocacy, and research Clinton Township, Michigan, USA . https://autoimmune.org) M Cutolo has been nominated to serve ACR as Abstract reviewer abstracts@rheumatology.org.
  • 2023: The American College of Rheumatology Annual Meeting Planning Committee like to formally invite you to serve as an abstract reviewer for the Immunological Complications of Medical Therapy Category. ACR23 ABSTRACTS SITE Abstract review will occur June 12 - July 3 2023. Username: mcutolo@unige.it 45 abstracts waiting for your review URL: https://www.abstractscorecard.com/cfp/review/login.asp?EventKey=INOAUXOA
  • 2024: The American College of Rheumatology Annual Meeting Planning Committee would like to formally invite you to serve as an abstract reviewer for the Immunological Complications of Medical Therapy Category (Lee Hutchison-Boughton (abstracts@rheumatology.org)
  • 2024: On behalf of the American College of Rheumatology (ACR) and the Association of Rheumatology Professionals (ARP) Membership and Awards Committee, MC received the ACR Master Designation as AWARD winner and presented during the Opening Ceremony of the 2024 ACR Annual Meeting (15th November in Washington).
  • 2024/2027: On behalf of the American College of Rheumatology (ACR) and the ACR Global Engagement Committee, we would like to sincerely congratulate you on being selected for to the role of ACR International Adviser. International Advisers (IAs) are the ACR’s local representatives around the world, engaging with international members, colleagues and organisations and helping to identify meaningful opportunities for collaboration. They provide advice and guidance on a range of professional, education and training, and socio-cultural issues, giving insight into health systems and local epidemiology.

Memberships and International Ranking

  • 1981 - ongoing: Elected member of the American Rheumatism Association (1981 ARA) then American College of Rheumatology (ACR #: 26378)
  • 1981 - ongoing: Elected member of the European League against Rheumatic Diseases (EULAR)
  • 2024: M Cutolo is ranked 42th amongst top Italian Scientists in Clinical Sciences (file:///Users/mcutolo/Desktop/Top%20Italian%20Scientists.webarchive)
  • 2023: M Cutolo is ranked 4463 amongst top 200.000 world scientists into 22 scientific fields (Second ranked for the whole University of Genova) August 2024 data-update for "Updated science-wide author databases of standardized citation indicators" - Elsevier BV (digitalcommonsdata.com) (https://dx.doi.org/10.17632/btchxktzyw Search: XLSX Table_1_Authors_career_2023_pubs_since_1788_wopp_extracted_202408.xlsx Published: 16 September 2024|Version 7 |DOI: 10.17632/btchxktzyw.7.
  • 2024: M Cutolo According to the Research.com, a leading academic platform for researchers, just released for the 2024 Edition of Ranking of Best Scientists in the field of Medicine is ranked #98 in Italy and #3944 in the world. The full ranking for Italy is available here: research.com/scientists-rankings/medicine/it The full world ranking is available here: research.com/scientists-rankings/medicine

Congress and Courses Organisation

  • 1998 up 2013: Organizer and Chairman of the 5 International Conferences on Neuroendocrine Immune Basis of the Rheumatic Diseases (NEIRD) in cooperation with ACR/NIH experts: G. Chrousos, A. Masi, R Wilder, L. Crofford (Santa Margherita 1998, 2001, 2005, 2009, 2013)
  • From 2003 - ongoing: Organizer and Co-Chairman of the Workshops/Skill Sessions on Capillaroscopy/Microcirculation and Rheumatic Diseases during the annual EULAR Congresses (Lisbon 2003, Berlin 2004, Vienna 2005, Amsterdam 2006, Barcelona 2007, Paris 2008, Copenhagen 2009, Rome 2010, London 2011, Berlin 2012, Madrid 2013, Paris 2014, Rome 2015, London 2016, Madrid 2017, Amsterdam 2018, Madrid 2019, Copenhagen 2022, Milan 2023,Vienna 2024 with https://www.eular.org )
  • From 2004 - ongoing: Organizer and Co-Chairman of the EULAR Live 3 days Courses on Capillaroscopy and Rheumatic Diseases (Genova 2004, 2006, 2008, 2010, 2012, 2013, 2014, 2016, 2018, Madrid 2019, Copenhagen 2022, Milan 2023, Vienna 2024 Average number of participants 110 from 32-45 Countries EULAR School of Rheumatology https://esor.eular.org)
  • 2009 and 2010: Organizer and Chairman of the 3 days EULAR Postgraduate Courses (Torre del Greco Naples - Italy)
  • 2020-2023: Organization and Co-Chair First EULAR (267 particpippants from 65 countries) and second online Course (243 participants from 60 countries) (7 modules) on Capillaroscopy and Microcirculation in rheumatic Diseases EULAR School of Rheumatology https://esor.eular.org)
  • 2024: Genova Organizer and Chairman of the 43rd European Workshop on Rheumatology Research (EWRR2024) (participants from 35 countries) endorsed by EULAR, Italian Society for Rheumatology (SIR), European Netwok on Rare and Complex Connective Tissue Diseases (ERN ReCONNET), University of Genova (UNIGE) (https://ewrr2024.com)

Editorial Board and Peer Review Responsibilities

  • 1983 - ongoing: Editorial Member, Associate Editor (from 2020) and now Senior Editor of Clinical and Experimental Rheumatology (Editor S. Bombardieri)
  • 1998 - 2008: Member of the Editorial Board of Rheumatology (Oxford)
  • 2002 - 2005: Member of the Advisory Board of Arthritis and Rheumatology (Editor D Pisetsky) Official Journal of ACR
  • 2003 - ongoing: Member of the Editorial Board of Annals of the Rheumatic Diseases Official Journal of EULAR (IF 2022, 27.4)
  • 2015 - ongoing: Member of the Editorial Board of RMD open Official Journal of EULAR
  • 2024: Co-Editor with S Bombardieri of the new Journal (May 2024) Journal of Environmental Rheumatology

In addition, past or present Editorial Board Member of: Current Opinion Rheumatology, Nutrients, Autoimmunity Review, Journal of Autoimmunity. Revista Portuguese de Reumatologia, Reumatismo, Arthritis Care & Res, Artrhritis Res & Therapy, Seminars in Arthritis and Rheumatism, Clinical Rheumatology

Note Upon invitation by the Editors, M Cutolo has served as author of informative articles for the Rheumatologist (i.e. “Why capillaroscopy in RMDs”), the official publication of the ACR and the ARP serving rheumatologists and rheumatology professionals (2008-2011)

Reviewer for: Nature Rev Rheumatology, Lancet, Nature Communications, NEJM, Lancet Rheumatology, Rheumatology (Oxford), Annals of Rheumatic Diseases, Arthritis and Rheumatism and several other Journals

Selection of chapters/modules in books and on line with authorship

Editor of the volumes of the Annals of the New York Academy of Sciences: “Neuroendocrine Immune Bssis of the Rheumatic Diseases” (vol 876/1999, vol 966/2002, vol 1069/200 and vol 1193/2010) CoEditor of the volumes of the of the Rheumatic Diseases Clinics of North America “Neuroendocrine Immunology of the Rheumatic Diseases” (Saunders) (vol 26:4/ 2000, vol 31:1/2005) CoEditor of the volume 22, issue 6: “Modern imaging techniques: a revolution for rheumatology practice”. Best Pract Res Clin Rheumatol (Elsevier) – 2008 Editor of the first textbook on capillaroscopy entitled: Atlas of capillaroscopy in Rheumatic Diseases - Elsevier 2010 under the aegis of EULAR. Author Chapter “Neuroendocrine immunology in rheumatic diseases” in the EULAR Compendium on Rheumatic Diseases (2009, chapt 50 BMJ and chapter 2 in the 2013 in the Kelley's Textbook of Rheumatology (2010-2011, chap 121), Author Chapter “Effects of the Neuroendocrine System on Development and Function of the Immune System” in Rheumatology - Fifth edition by Marc C. Hochberg, Alan J. Silman, Josef S. Smolen, Michael E. Weinblatt, MD, and Michael H. Weisman, MD. (2010, chap 24, Elsevier). - Varga J, ed. Scleroderma: From pathogenesis to Comprehensive Management. New York: Springer Science+Business Media, LLC. 2012. Chapter: Co-author Cutolo M, Smith V. Nailfold Capillaroscopy, p 331-346. Co-Author 1st EULAR On-line Course on Systemic Sclerosis September 2011 - June 2012. Module: 3. Co-author Assessment tools of the microcirculation. Cutolo M & Smith V, Editors Novel insights into systemic sclerosis management. Future Science Group. 2013. 3rd EULAR On-line Course in Systemic Sclerosis September 2013 – June 2013. Module: 3. Co-Authors Cutolo M, Smith V. Nailfold capillaroscopy and other methods to assess the microvasculopathy in systemic sclerosis. Hachulla E & Czirjak L, eds. EULAR Textbook on Systemic Sclerosis. BMJ. 2013.Chapter: 14. Co-Authors Cutolo M, Smith V. Nailfold capillaroscopy and other methods to assess the microvasculopathy in systemic sclerosis, p 129-138 - Wigley F et al, eds. Raynaud’s Phenomenon – A guide to Pathogenesis and Treatment. Springer Publishing. 2014. Chapter: 10c. Co-Authors Cutolo M, Smith V. Nailfold capillaroscopy. Co-Editor 2021-2023 of the First EULAR on line Course on Capillaroscopy and Microcirculation in RMDs (7 modules). Co-Editor from 2019 and updates of the First EULAR Module on line on Nutrition in RMD. Editor from 2020.of the Special Issues of the Journal Nutrients: Vitamin D and autoimmunity.

Major and seminal topics of Research

Neuroendocrine Immunology of Rheumatic Diseases (NEIRD)

M Cutolo and TEAM have produced original and seminal research on NEIRD since 1990, with the original discovery of sex hormone functional receptors on rheumatoid arthritis (RA) synovial macrophages. M Cutolo showed that cultured macrophages metabolise sex hormones up to the active metabolites and modulate the immune response On the other hands, circadian rhythms drive during the night the immune system activation through hormones mainly cortisol, and in particular conditions of their deficiency like time in inflammatory diseases such as RA, the immune response at night is not dowregulated. To this purpose, for instance, the study of presence of adrenocortical insufficiency (related to the chronic stress induced by the diseases) through baseline dynamic testing of adrenal function, adrenal glucocorticoids and steroids circadian evaluation, induced to the production of the first programmed release prednisone following the researches of the Cutolo Team since from 2000.

Cutolo M et al. Presence of estrogen-binding sites on macrophage-like synoviocytes and CD8+, CD29+, CD45RO+ T lymphocytes in normal and rheumatoid synovium. Arthritis Rheum. 1993 Aug;36(8):1087-97 Cutolo M, Straub RH, Bijlsma JW.Neuroendocrine-immune interactions in synovitis. Nature Clin Pract Rheumatol. 2007 Nov;3(11):627-34. Straub RH, Bijlsma JW, Masi A, Cutolo M. Role of neuroendocrine and neuroimmune mechanisms in chronic inflammatory rheumatic diseases--the 10-year update. Semin Arthritis Rheum. 2013 Dec;43(3):392-404. Cutolo M et al. Circadian rhythms in RA. Ann Rheum Dis. 2003 Jul;62(7):593-6 Straub RH & Cutolo M. Circadian rhythms in rheumatoid arthritis: implications for pathophysiology and therapeutic management. Arthritis Rheum. 2007 Feb;56(2):399-408

Cutolo M. Rheumatoid arthritis: circadian and circannual rhythms in RA. Nature Rev Rheumatol. 2011 Aug 2;7(9):500-2.

Burmester GR, Bijlsma JWJ, Cutolo M, McInnes IB. Managing rheumatic and musculoskeletal diseases - past, present and future. Nature Rev Rheumatol. 2017 Jul;13(7):443-448. Cutolo M, Straub RH. Sex steroids and autoimmune rheumatic diseases: state of the art. Nature Rev Rheumatol. 2020 Nov;16(11):628-644.

Identification of M1/M2 phenotypes in rheumatoid arthritis and systemis sclerosis

M Cutolo and TEAM have first evaluated the transition of M1/M2 macrophages from RA patients and their in vitro modulation linked to the disease status. Then, have identified for the first time, the phenotypes of circulating monocytes and lung and skin derived macrophages in systemic sclerosis (SSc). In particular, the transition from macrophages M1 to M2 has been evaluted in vitro studies, as well as the cell membrane and functional markers that identify the M1 and M2 when modulated by drugs. A particular circulating monocyte phenotype M1/M2 has been detected for the first time in SSc patients.

Tardito S ..and Cutolo M. Macrophage M1/M2 polarization and rheumatoid arthritis. Autoimmun Rev. 2019 Nov;18(11):102397 Cutolo M et al. CTLA4-Ig treatment induces M1-M2 shift in cultured monocyte-derived macrophages from healthy subjects and rheumatoid arthritis patients. Arthritis Res Ther. 2021 Dec 24;23(1) Soldano S.. and Cutolo M. Increase in circulating cells coexpressing M1 and M2 macrophage surface markers in patients with systemic sclerosis. Ann Rheum Dis. 2018 Dec;77(12):1842-1845. Trombetta AS.. and Cutolo M. A circulating cell population showing both M1 and M2 monocyte/macrophage surface markercharacterizes systemic sclerosis patients with lung involvement. Respir Res. 2018 Sep 24;19(1):186

Focalised research on the effects of the secosteroid vitamin D deficiency in infections (COVID-19) and autoimmunity

M Cutolo and TEAM have for the first time deeply investigated the role of calcitriol (1,25(OH)2 D3) deficiency in autoimmune RMDs (ARDs) and in COVID patients. The endogenous serum metabolite of vitamin D (calcitriol) is considered a true steroid hormone (D hormone), and like glucocorticoids (GCs) and gonadal hormones, may exert several immunomodulatory activities. Serum vitamin D deficiency (25(OH) D), and therefore reduced 1,25(OH)2 D3 availability, is considered a risk factor for several chronic/inflammatory or autoimmune conditions, including infectious diseases, type 1 diabetes, multiple sclerosis, and especially autoimmune rheumatic diseases (ARD). In ARD in particular, 1,25(OH)2 D3 regulates both innate and adaptive immunity, potentiating the innate response (antimicrobial activity) but reducing adaptive immunity (antigen presentation, T and B cell activities). Conversely, vitamin D deficiency seems to play a role in increasing autoantibody production by B cells, and seasonal vitamin D declines may trigger flares in ARDs, as recently shown.). Dramatic the effects of calcitriol deficiency in COVID-19 patients and SARSCov2 infection as risk factor for disease severity and dead.

Cutolo M et al. Circannual vitamin D serum levels and disease activity in rheumatoid arthritis: Northern versus Southern Europe. Clin Exp Rheumatol. 2006 Nov-Dec;24(6):702-4 Cutolo M et al. Vitamin D involvement in rheumatoid arthritis and systemic lupus erythaematosus. Ann Rheum Dis. 2009 Mar;68(3):446-7 Cutolo M. Further emergent evidence for the vitamin D endocrine system involvement in autoimmune rheumatic disease risk and prognosis. Ann Rheum Dis. 2013 Apr;72(4):473-5 Cutolo M et al. Evidences for a protective role of vitamin D in COVID-19.RMD Open. 2020 Dec;6(3):e001454.

Sulli A .. and Cutolo M. Nutrients. 2021 Feb 24;13(3):717. Cutolo M et al. Involvement of the secosteroid vitamin D in autoimmune rheumatic diseases and COVID-19. Nature Rev Rheumatol. 2023 May;19(5):265-287

Definition of nailfod video capillaroscopy patterns in systemic sclerosis and prognostic role

M Cutolo and TEAM proposed for the first time in 2000 a new classification for the microvascular patterns (early, active, late) observed in SSc based on the nailfold video Capillaroscopy (NVC). NVC is today mandatory for the early differential diagnosis between benign Raynaud’s phenomenon and RP associated to SSc. Furthermore, based on the qualtification of the NVC changes it is possible a prediction of clinical complications in Connective tissues Diseases mainly in SSc and related lung and skin involvement. Also and logically, in SSc, microangiopathy, as assessed by NVC, has been associated with markers of the disease such as angiogenic/static factors and SSc-specific antibodies. Moreover, morphological assessments of the microcirculation (capillaroscopy) correlates with functional assessments of peripheral blood flow (such evaluated by aser Doppler). From those studies the European League Against Rheumatism (EULAR) and the American College of Rheumatology (ACR) introduced in 2013 the NCV analysis among the criteria for the classification of SSc.


Cutolo M, Sulli A, Smith V. Assessing microvascular changes in systemic sclerosis diagnosis and management. Nature Rev Rheumatol. 2010 van den Hoogen F et al. 2013 classification criteria for systemic sclerosis: an American College of Rheumatology/European League against Rheumatism collaborative initiative. Arthritis Rheum. 2013 Nov;65(11):2737-47

Cutolo M et al. Nailfold Videocapillaroscopic Features and Other Clinical Risk Factors for DigitalUlcers in Systemic Sclerosis: A Multicenter, Prospective Cohort Study. CAP Study Investigators. Arthritis Rheum 2016 Oct;68(10):2527-39

Cutolo M, Sulli A.Therapy. Optimized treatment algorithms for digital vasculopathy in SSc. Nature Rev Rheumatol. 2015 Oct;11(10):569-71 Cutolo M et al. Nailfold Videocapillaroscopic Features and Other Clinical Risk Factors for DigitalUlcers in Systemic Sclerosis: A Multicenter, Prospective Cohort Study. CAP Study Investigators. Arthritis Rheumatol. 2016;68(10):2527-39. Oliver Distler 1et al. Cutolo M. Nintedanib for Systemic Sclerosis-Associated Interstitial Lung Disease. N Engl J Med 2019 Jun 27;380(26):2518-2528. Cutolo M, Smith V. Detection of microvascular changes in systemic sclerosis and other rheumatic diseases. Nature Rev Rheumatol. 2021 Nov;17(11):665-677.

Bellando Randone S.......Cutolo M et al. Progression of patients with Raynaud’s phenomenon to systemic sclerosis: a five-year analysis of the European Scleroderma Trial and Research group multicentre, longitudinal registry study for Very Early Diagnosis of Systemic Sclerosis (VEDOSS) Lancet Rheumatol 2021 3: e834–43

Scientific production

M Cutolo has produced more than 786 peer reviewed papers listed in PUB MED.

M Cutolo actual H Index 124 (Google Scholar more than 71,449 citations) and 100 (Scopus more than 47,000 citations) (November 2024)

International Mentorship

From 2008 up now M Cutolo has hosted and acted as mentor for 87 people, among them medical students, postgraduates, research fellows, PhD, rheumatologists, EULAR and ERASMUS Scholars, professors for internship at the Research Laboratory of Experimental Rheumatology or at the Clinical Division of Rheumatology for periods ranging from 2 weeks up to 24 months.

The countries of origin of the fellows were: UK, Canada, China, Russia, Germany, South Africa, Brasil, Israel, Japan, Brasil, Peru, Australia, Portugal, Albania, Rumania, Estonia, Latvia, Sweden, Finland, Croatia, Poland, Greece, Ukraine, Jordan, Chile, Hong Kong, Moldovia, Serbia, Colombia, France, Russia, Hungary, Egypt, Argentina, Bolivia, Mexico, Turkey, Spain, Irland, Belgium, Malaysia.

The original documents and CV of each fellow are available.

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