Gaetano Rocco: Difference between revisions
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* 2022: Honorary Membership (Life Achievement Award) European Society of Thoracic Surgeons. | * 2022: Honorary Membership (Life Achievement Award) European Society of Thoracic Surgeons. | ||
== Publications == | |||
=== Notable publications === | |||
* 20 most important publications | |||
=== Chapters === | |||
# General Thoracic Surgery TW Shields LWW 7th Edition: Surgical Anatomy of the Lungs/ Mediastinal Cysts. | |||
# Thoracic Surgery Pearson FG Churchill and Livingstone: Empyema. | |||
# Surgery of the Chest Sabinston and Spencer: Chylothorax. | |||
# Difficult Decisions in Thoracic Surgery – An Evidence based approach – Second Edition, Ferguson M Editor-Springer Publisher. “Lobectomy after induction therapy for stage IIIA NSCLC in the presence of persistent N2 disease.” 2011; 111-17 | |||
# Rocco G. Anterior chest wall resection and reconstruction. Oper Tech Thorac Cardiovasc Surgy. 2013;18(1):32-41. | |||
# Difficult Decisions in Thoracic Surgery – An Evidence based approach – Third Edition, Ferguson M Editor-Springer Publisher. “Syntethic vs biologic reconstruction of bony chest wall defects.” 2014. | |||
# Chirurgia Toracica Videoassistita – Principi, Indicazione e Tecniche – Lavini C, Ruggiero C, Morandi U Eds. – Springer Publisher. “Chirurgia Videoassistita del diaframma”2006; 298-302. | |||
# Oncologia Toracica-Carpagnano F Ed. “Risultati nel trattamento chirurgico del NSCLC localmente avanzato. 2007; 203-208. | |||
# Rocco G. Synthetic versus biologic reconstruction of bony chest wall defects. In: Ferguson M, ed. Difficult Decisions in Thoracic Surgery. Difficult Decisions in Surgery: An Evidence-Based Approach. Springer; 2014. | |||
# Rocco G. VATS wedge resection. In: Dienemann H, Hoffmann H, Detterbeck F, eds. Chest Surgery. Springer Surgery Atlas Series. Springer; 2015. | |||
# Rocco G, De Luca G. Staging of lung cancer. In: Coonar A, Wells F, Scarci M, Routledge T, eds. Core Topics in Thoracic Surgery. Cambridge University Press; 2016. | |||
# Moradiellos FJ, Seder CW, Rocco G. Chest wall resection and reconstruction. In: Scarci M, Sihoe ADL, Bedetti B, eds. Open Thoracic Surgery. AME Publishing Company; 2017. | |||
# Rocco G. Uniportal video-assisted thoracoscopic surgery (VATS). In: Jamieson G, Kaiser LR, Thompson SK, eds. Operative Thoracic Surgery. CRC Press; 2017: 205-212. | |||
# Ottlakan A, Martucci N, Rocco G. Is surgery still the best management option for early stage NSCLC? In: Song Y, Folch E, G Rocco, HH Popper, eds. Pulmonary Nodules and Lung Cancer. AME Publishing; 2017. | |||
# Luca GD, Martucci N, Rocco G. Cysts of the middle mediastinum. In: Franco R, Zito Marino F, Giordano A, eds. The Mediastinal Mass. Humana Press; 2018: 261-269. | |||
# Martucci N, Luca GD, Rocco G. Granulomatous disease. In: Franco R, Zito Marino F, Giordano A, eds. The Mediastinal Mass. Humana Press; 2018: 253-260. | |||
# Luca GD, Martucci N, Rocco G. In: Franco R, Zito Marino F, Giordano A, eds. The Mediastinal Mass. Humana Press; 2018: 271-276. | |||
# Scarci M, Minervini F, Rocco G. Uniportal video-assisted thoracoscopic surgery for the management of pleural effusions, empyema and pleural biopsy. In: Gonzalez-Rivas D, Ng CSH, Rocco G, D’Amico TA, eds. Atlas of Uniportal Video Assisted Thoracic Surgery. Springer; 2019: 47-49. | |||
# Rocco G, Rocco R, Scarci M. Intraoperative ultrasound guidance in pulmonary nodule localization in uniportal VATS. In: Gonzalez-Rivas D, Ng CSH, Rocco G, D’Amico TA, eds. Atlas of Uniportal Video Assisted Thoracic Surgery. Springer; 2019: 101-102. | |||
# Scarci M, Minervini F, Rocco G. Videoendoscopic uniportal resection of solitary peripheral lung nodule. In: Gonzalez-Rivas D, Ng CSH, Rocco G, D’Amico TA, eds. Atlas of Uniportal Video Assisted Thoracic Surgery. Springer; 2019: 103-106. | |||
# Gritsiuta AY, Eguchi T, Jones DR, Rocco G. A stepwise approach for postlobectomy bronchopleural fistula. Operative Techniques in Thoracic and Cardiovascular Surgery, Vol. 25, Issue 2, p85–104. 2019. | |||
# Gray KD, Rocco G. Meediastinoscopy. Pearson’s Thoracic and Esophageal Surgery. 2019 [In press]. | |||
# Sotiropoulos G, Rocco R, Sideris A, Rocco G. Chylothorax. Sabiston and Spencer Surgery of the Chest. 10th edition. 2021 [In press]. | |||
# Rocco G, Shahzad F, Bains MS, Mehrara B. Chest Wall Resection and Reconstruction. Fischer’s Mastery of Surgery, Eighth Edition. 2022 [In press]. | |||
# Rocco G, Deschamps C, Deslauriers J. Fibrothorax And Decortication. STS Cardiothoracic Surgery E-Book. 2022 [In press]. | |||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 16:29, 9 March 2023
Gaetano Rocco (born July 15, 1960, Milan, Italy). He is Director, Chest Wall Surgery Program and Attending Surgeon at the MSKCC, New York, NY[1].
| Born |
| July 15, 1960, Milan, Italy |
| Nationality |
| Italian |
| Education |
| MD, University of Milan, Italy |
| Fields |
| Thoracic Surgery, Translational medicine, Clinical guidelines, Minimally invasive thoracic surgery |
| Institutions |
| Director, Chest Wall Surgery Program, MSKCC, New York, NY |
| Attending Surgeon, MSKCC, New York, NY |
| Notes |
| Top Italian Scientist in Clinical Sciences [2] |
Education and career
Academic Degree
- 1985: MD, University of Milan, Italy.
Post-doctoral training =
- 1984, 1986, 1987-1988: Research Fellow in Surgical Pathology, Stritch School of Medicine, Loyola University, Chicago, IL.
- 1985-1990: Resident, General Surgery, University of Milan Hospitals, Milan, Italy.
- 1990-1995: Resident, Thoracic Surgery, University of Milan Hospitals, Milan, Italy.
- 1995: Visiting Resident, Section of General Thoracic Surgery, Mayo Clinic and Mayo Foundation, Rochester, MN.
- 1996-1997: Clinical Fellow in Advanced General Thoracic Surgery, Section of General Thoracic Surgery, Mayo Clinic and Mayo Foundation, Rochester, MN.
- 1999: Fellowship in Laparoscopic Surgery, University of Strasbourg, France, on behalf of the European Institute of Telesurgery (EITS), Strasbourg, France.
- 2000: Research Fellow, British Mesothelioma Group, British Lung Volume Reduction Group.
- 2003: Research Fellow, MRC LU-22.
Career
Academic positions
- 1992: Professor of Surgery, E. Morelli Regional Hospital, Nursing School, Sondalo, Italy.
- 1993-1999: Professor of Thoracic Surgery, E. Morelli Regional Hospital, Nursing School, Sondalo, Italy.
- 2000-2004: Hon. Senior Clinical Lecturer, Department of Cardiothoracic Surgery, Northern General Hospital, Sheffield Teaching Hospitals, Sheffield, UK.
- 2004-2006: Faculty, European School for Cardiothoracic Surgery, Bergamo level II.
- 2011-2018: Professor of Thoracic Surgery, University of Naples, Italy.
- 2011-2018: Professor of Cardiothoracic Surgery, University of Naples, Italy.
- 2012-2018: Professor of Thoracic Surgery University of Bari, Italy.
Hospital positions
- 1988-1999: Staff Thoracic Surgeon, E. Morelli Regional Hospital, Sondalo, Italy.
- 2000-2004: Consultant Thoracic Surgeon, Department of Cardiothoracic Surgery, Northern General Hospital, Sheffield Teaching Hospitals, Sheffield, UK.
- 2004-2018: Chief, Division of Thoracic Surgery, National Cancer Institute, Pascale Foundation, Naples, Italy.
- 2008-2018: Head, Department of Thoracic Surgery and Oncology, National Cancer Institute, Pascale Foundation, Naples, Italy,
- 2018-Present: Attending Surgeon, MSKCC, New York, NY.
- 2021-Present: Director, Chest Wall Surgery Program, MSKCC, New York, NY
Other Employment
- 1986-1987: Medical Officer, Italian Army.
Research
Clinical Trials
- ITACA EudraCT n. 2008-001764-36 “Phase III Multicenter Randomized Trial Comparing Adjuvant Pharmacogenomic-Driven Chemotherapy versus Standard Adjuvant Chemotherapy in Completely Resected Stage II-IIIA Non-Small Cell Lung Cancer” Start date: 2008 – Institutional co-Principal Investigator.
- MILES-3 Cisplatin in Combination With Gemcitabine for Elderly Patients With Stage IIIB-IV Non Small Cell Lung. Role: Surgical Investigator.[3]
- MILES-4 Study Comparing Gemcitabine and Pemetrexed, With or Without Cisplatin, in Elderly Patients With Advanced Nonsquamous Lung Cancer. Role: Surgical Investigator.[3]
- PETRA. Study of Metabolic Response measured with PET/CT after the first cycle of chemotherapy in patients with Advanced Non Small Cell Lung Cancer. Role: Surgical Investigator.
- ERACLE GOIM Protocol 2903. Induction Pemetrexed and Cisplatin Followed by Pemetrexed as Maintenance vs Carboplatin-paclitaxel and Bevacizumab Followed by Bevacizumab as Maintenance: Multicenter Randomized Phase III Study in Patients With Advanced Non-Squamous Non Small-cell Lung Cancer. Role: Surgical Investigator.[3]
- ARQ197. A phase 3, randomized, double-blinded, placebo controlled, study of ARQ197 plus erlotinib versus erlotinib plus placebo in previously treated subjects with locally advanced or metastatic non-squamous non small cell lung cancer (NSCLC). Role: Surgical Investigator.[3]
- INSPIRE. A randomized, multicenter, open-label phase 3 study of pemetrexed-cisplatin chemotherapy plus IMC-11F8 versus pemetrexed-cisplatin chemotherapy alone in the first line treatment of patients with non squamous stage IIIB or IV Non-Small Cell Lung Cancer (IMCL CP11-0805; INSPIRE). Role: Surgical Investigator.[3]
- SQUIRE. A randomized, multicenter, open-label phase 3 study of gemcitabine-cisplatin chemotherapy plus IMC-11F8 versus gemcitabine-cisplatin chemotherapy alone in the first line treatment of patients with squamous stade IIIB or IV Non-Small Cell Lung Cancer (IMCL CP11-0806;SQUIRE). Role: Surgical Investigator.[3]
- Phase 2, open label single arm study of the efficacy and safety of PF-02341066 in patients with advanced non-small cell lung cancer harbouring a translocation or inversion involving the anaplastic lymphoma kinase (ALK) gene locus. Role: Surgical Investigator
- Phase 3, randomized open-label study of the efficacy and safety of PF-02341066 versus standard of care chemotherapy (pemetrexed or docetaxel) in patients with advanced non-small cell lung cancer harbouring a translocation or inversion involving the anaplastic lymphoma kinase (ALK) gene locus. Role: Surgical Investigator.
- NCIC CTG BR.26. A double blind placebo controlled trial of PF-804 in patients with incurable stage IIIB/IV NSCLC after failure of standard therapy for advanced or metastatic disease (NCIC CTG BR.26). Role: Surgical Investigator.[3]
- LUX-Lung 8 - A Randomized, Open-label Phase III Trial of Afatinib Versus Erlotinib in Patients With Advanced Squamous Cell Carcinoma of the Lung as Second-line Therapy Following First-line Platinum-based Chemotherapy. Role: Surgical Investigator.[3]
- ICARUS. A Phase II Open Label, Multicentre, Single Arm Study to Characterise the Efficacy, Safety and Tolerability of Gefitinib 250 mg (IRESSA) as 3rd Line Treatment Re-challenge in Patients, Who Have Epidermal Growth Factor Receptor (EGFR) Mutation Positive Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) and Who Responded to Gefitinib in 1st Line and Progressed After 2nd Line Chemotherapy (Studio ICARUS). Role: Surgical Investigator.[3]
- AVALL MO22097. An open-label, randomized, Phase IIIb trial evaluating the efficacy and safety of continuous bevacizumab treatment beyond progression of disease (PD) in patients with advanced non-squamous non-small cell lung cancer (NSCLC) after first (1st)-line treatment with bevacizumab plus a platinum doublet-containing chemotherapy regimen (AVALL - Roche). Role: Surgical Investigator.
- ASSESS. A diagnostic Study of European and Japanese advanced NSCLC patients to evaluate suitable sample types for EGFR testing: The ASSESS Study (Astra Zeneca). Role: Surgical Investigator.[3]
- BASALT 2. A Dose-finding phase Ib study followed by a randomized, double-blind phase II study of carboplatin and paclitaxel with or without buparlisib in patients with previously untreated metastatic non-small cell lung cancer (NSCLC) of squamous histology (BASALT 2 – Novartis). Role: Surgical Investigator.[3]
- BASALT 3. A Phase Ib/II study of docetaxel with or without buparlisib as second line therapy for patients with advanced or metastatic squamous non-small cell lung cancer (BASALT 3 - Novartis). Role: Surgical Investigator.[3]
- Phase I Study of single agent MK-3475 in patients with progressive locally advanced or metastatic carcinoma, melanoma, and non-small cell lung carcinoma (MERK). Role: Surgical Investigator
- Observational study “E-Lung”. Lung cancer: from patient’s needs, the answers from oncology. Role: Surgical Investigator.
- ARCHER Study A7471009: a randomized double blind phase 3 efficacy and safety study of PF-00299804 versus erlotinib for the treatment of advanced non-small cell lung cancer following progression after, or intolerance to, at least one prior chemotherapy (ARCHER 1050 – Pfizer). Role: Surgical Investigator.[3]
- SELECT-1. A phase III, double-blind, randomized, placebo-controlled study to assess the efficacy and safety of selumetinib (AZD6244) in combination with docetaxel in patients receiving second line treatment for KRAS mutation-positive locally advanced or metastatic non small cell lung cancer (stage IIIB – IV) (SELECT-1 – Astra Zeneca). Role: Surgical Investigator.[3]
- An open label trial of afatinib in treatment-naïve (1st line) or chemotherapy pre-treated patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) harboring EGFR mutation(s). Role: Surgical Investigator.
- BR-31 A PHASE III PROSPECTIVE DOUBLE BLIND PLACEBO CONTROLLED RANDOMIZED STUDY OF ADJUVANT MEDI4736 IN COMPLETELY RESECTED NON-SMALL CELL LUNG CANCER.[3] Role: Principal Investigator.
Honors and awards
- 2006: Silver Medal “Aesculapius” of the Italian Minister of Health for Professional Achievements.
- 2011: Alumnus d'Honore from Hopital Marie-Lannelongue, Universite Sud, Paris, France.
- 2016: Listed in “Top Italian Scientists” website.
- 2022: Honorary Membership (Life Achievement Award) European Society of Thoracic Surgeons.
Publications
Notable publications
- 20 most important publications
Chapters
- General Thoracic Surgery TW Shields LWW 7th Edition: Surgical Anatomy of the Lungs/ Mediastinal Cysts.
- Thoracic Surgery Pearson FG Churchill and Livingstone: Empyema.
- Surgery of the Chest Sabinston and Spencer: Chylothorax.
- Difficult Decisions in Thoracic Surgery – An Evidence based approach – Second Edition, Ferguson M Editor-Springer Publisher. “Lobectomy after induction therapy for stage IIIA NSCLC in the presence of persistent N2 disease.” 2011; 111-17
- Rocco G. Anterior chest wall resection and reconstruction. Oper Tech Thorac Cardiovasc Surgy. 2013;18(1):32-41.
- Difficult Decisions in Thoracic Surgery – An Evidence based approach – Third Edition, Ferguson M Editor-Springer Publisher. “Syntethic vs biologic reconstruction of bony chest wall defects.” 2014.
- Chirurgia Toracica Videoassistita – Principi, Indicazione e Tecniche – Lavini C, Ruggiero C, Morandi U Eds. – Springer Publisher. “Chirurgia Videoassistita del diaframma”2006; 298-302.
- Oncologia Toracica-Carpagnano F Ed. “Risultati nel trattamento chirurgico del NSCLC localmente avanzato. 2007; 203-208.
- Rocco G. Synthetic versus biologic reconstruction of bony chest wall defects. In: Ferguson M, ed. Difficult Decisions in Thoracic Surgery. Difficult Decisions in Surgery: An Evidence-Based Approach. Springer; 2014.
- Rocco G. VATS wedge resection. In: Dienemann H, Hoffmann H, Detterbeck F, eds. Chest Surgery. Springer Surgery Atlas Series. Springer; 2015.
- Rocco G, De Luca G. Staging of lung cancer. In: Coonar A, Wells F, Scarci M, Routledge T, eds. Core Topics in Thoracic Surgery. Cambridge University Press; 2016.
- Moradiellos FJ, Seder CW, Rocco G. Chest wall resection and reconstruction. In: Scarci M, Sihoe ADL, Bedetti B, eds. Open Thoracic Surgery. AME Publishing Company; 2017.
- Rocco G. Uniportal video-assisted thoracoscopic surgery (VATS). In: Jamieson G, Kaiser LR, Thompson SK, eds. Operative Thoracic Surgery. CRC Press; 2017: 205-212.
- Ottlakan A, Martucci N, Rocco G. Is surgery still the best management option for early stage NSCLC? In: Song Y, Folch E, G Rocco, HH Popper, eds. Pulmonary Nodules and Lung Cancer. AME Publishing; 2017.
- Luca GD, Martucci N, Rocco G. Cysts of the middle mediastinum. In: Franco R, Zito Marino F, Giordano A, eds. The Mediastinal Mass. Humana Press; 2018: 261-269.
- Martucci N, Luca GD, Rocco G. Granulomatous disease. In: Franco R, Zito Marino F, Giordano A, eds. The Mediastinal Mass. Humana Press; 2018: 253-260.
- Luca GD, Martucci N, Rocco G. In: Franco R, Zito Marino F, Giordano A, eds. The Mediastinal Mass. Humana Press; 2018: 271-276.
- Scarci M, Minervini F, Rocco G. Uniportal video-assisted thoracoscopic surgery for the management of pleural effusions, empyema and pleural biopsy. In: Gonzalez-Rivas D, Ng CSH, Rocco G, D’Amico TA, eds. Atlas of Uniportal Video Assisted Thoracic Surgery. Springer; 2019: 47-49.
- Rocco G, Rocco R, Scarci M. Intraoperative ultrasound guidance in pulmonary nodule localization in uniportal VATS. In: Gonzalez-Rivas D, Ng CSH, Rocco G, D’Amico TA, eds. Atlas of Uniportal Video Assisted Thoracic Surgery. Springer; 2019: 101-102.
- Scarci M, Minervini F, Rocco G. Videoendoscopic uniportal resection of solitary peripheral lung nodule. In: Gonzalez-Rivas D, Ng CSH, Rocco G, D’Amico TA, eds. Atlas of Uniportal Video Assisted Thoracic Surgery. Springer; 2019: 103-106.
- Gritsiuta AY, Eguchi T, Jones DR, Rocco G. A stepwise approach for postlobectomy bronchopleural fistula. Operative Techniques in Thoracic and Cardiovascular Surgery, Vol. 25, Issue 2, p85–104. 2019.
- Gray KD, Rocco G. Meediastinoscopy. Pearson’s Thoracic and Esophageal Surgery. 2019 [In press].
- Sotiropoulos G, Rocco R, Sideris A, Rocco G. Chylothorax. Sabiston and Spencer Surgery of the Chest. 10th edition. 2021 [In press].
- Rocco G, Shahzad F, Bains MS, Mehrara B. Chest Wall Resection and Reconstruction. Fischer’s Mastery of Surgery, Eighth Edition. 2022 [In press].
- Rocco G, Deschamps C, Deslauriers J. Fibrothorax And Decortication. STS Cardiothoracic Surgery E-Book. 2022 [In press].